Publications by authors named "D Paramythiotis"
Colorectal cancer is the third most common malignancy, with around half of patients developing liver metastases. Hepatectomy is the preferred treatment, but its success depends on several factors, including surgical margins. Various surgical margins have been suggested to achieve optimal results.
View Article and Find Full Text PDF: Acute necrotizing pancreatitis (ANP) is the acute inflammation of pancreatic parenchyma, most commonly due to alcohol abuse or cholelithiasis. The treatment can be either conservative or invasive, including a variety of techniques; however, it has not yet been established if the intervention should be early or if it should be delayed. The aim of this review is to investigate the optimal time for intervention in ANP.
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- Autoimmune pancreatitis (AIP) is a rare form of chronic pancreatitis caused by autoimmune dysfunction, classified into three subtypes, with type 1 and type 2 responding well to corticosteroids.
- A case study presented a patient with symptoms resembling pancreatic cancer, where imaging suggested obstruction, leading to a Whipple surgery; however, the pathology indicated AIP type 1 instead.
- This highlights the importance of thorough preoperative assessments to avoid unnecessary surgeries, as AIP can be misdiagnosed, emphasizing its relevance in clinical practice.
Article Synopsis
- Colorectal surgery for cancer carries a significant risk of complications like anastomotic leakage, making it important to predict this risk early for personalized treatment plans and reduced hospitalization times.* -
- The study evaluated the neutrophil-to-lymphocyte ratio (NLR) in 245 colorectal surgery patients, finding that an NLR of ≥ 7.4 on postoperative day 1 can reliably identify low-risk patients for leakage, while an NLR of ≥ 6.5 on postoperative day 4 is useful for identifying high-risk patients.* -
- The results suggest that using NLR measurements from day 1 can help doctors focus on patients who may need closer monitoring for leakage, improving patient management and outcomes
Article Synopsis
- Pancreatic cancer is a serious health concern, being the fourth deadliest cancer, but not all pancreatic masses are malignant, highlighting the need for accurate diagnosis through biopsy.
- This meta-analysis compares two minimally invasive biopsy methods for pancreatic tissue: percutaneous biopsies guided by imaging versus transduodenal biopsies using endoscopic ultrasound (EUS).
- Results show that the percutaneous approach is statistically superior in sensitivity and specificity, but biases in tumor selection may affect these findings, making the choice of biopsy method dependent on various clinical factors.