The Price of Love: Understanding the Financial and Psychosocial Costs of Caring for Children with Medical Complexities.

Parents of children with medical complexities (CMCs) report significant challenges affecting their financial, emotional and social well-being in relation to caring for their child's medical needs. The Complex Care Navigator Program was designed to provide social, emotional and economic support to parents of CMCs. This paper describes the results and outcomes of the program and the challenges experienced during the evaluation process.

Hydraulic Conductivity from Nuclear Magnetic Resonance Logs in Sediments with Elevated Magnetic Susceptibilities.

This study examined the application of slim-hole nuclear magnetic resonance (NMR) tools to estimate hydraulic conductivity (K ) in an unconsolidated aquifer that contains a range of grain sizes (silt to gravel) and high and variable magnetic susceptibilities (MS) (10 to 10 SI). A K calibration dataset was acquired at 1-m intervals in three fully screened wells, and compared to K estimates using the Schlumberger-Doll research (SDR) equation with published empirical constants developed from previous studies in unconsolidated sediments. While K using published constants was within an order of magnitude of K, the agreement, overprediction, or underprediction of K varied with the MS distribution in each well.

Helping Families Thrive: Co-Designing a Program to Support Parents of Children with Medical Complexity.

Families of children with medical complexity (CMC) face significant challenges beyond those related to caring for their child's medical condition. Parents of CMC report a variety of concerns impacting their social, emotional and financial well-being. This paper details how CHEO, community organizations and parents co-designed and evaluated the Navigator Program.

Arginase Is Essential for Survival of Leishmania donovani Promastigotes but Not Intracellular Amastigotes.

Studies of Leishmania donovani have shown that both ornithine decarboxylase and spermidine synthase, two enzymes of the polyamine biosynthetic pathway, are critical for promastigote proliferation and required for maximum infection in mice. However, the importance of arginase (ARG), the first enzyme of the polyamine pathway in Leishmania, has not been analyzed in L. donovani To test ARG function in intact parasites, we generated Δarg null mutants in L.

[Surgical treatment of ulcerative colitis].

Surgery for patients suffering from inflammatory bowel diseases is an option when medication-based treatment fails. Sometimes complex and carried out in several stages, the procedures require the nurses to be involved in the education of the patient, monitoring prevention and identification of complications.