The accurate determination of Perfluorooctane sulfonic acid (PFOS) removal efficiency by integrated-sonochemical system.

Perfluorooctanesulfonic acid (PFOS) is one of the most investigated Per- and polyfluoroalkyl substances (PFAS) for being the strongest compound to eliminate and having adverse health concerns. In this work, we have conducted the sonochemical treatment of PFOS simulated water under high (500 kHz) and low (22 kHz) frequencies while monitoring the operational parameters via an integrated sonochemical system. The integrated advanced sonochemical system includes software to monitor treatment power, solution temperature and frequency while allowing distinctive control of the reaction conditions.

Solar Assisted Mitigation of Chloramphenicol and H Evolution Using CuNi Alloy Nanoparticles on h-BN Doped g-CN: A Comprehensive Approach Combining Synchrotron and DFT Analysis.

A simple one-step deposition-precipitation method was used to synthesize highly active and well-defined CuNi alloy bimetallic nanoparticles supported on h-BN/g-CN. The nanocomposite was applied for hydrogen gas evolution via seawater splitting and photocatalytic chloramphenicol (CHP) removal. Through TEM and synchrotron studies, the formation of CuNi alloy and uniform distribution of CuNi bimetallic nanoparticles on the h-BN/g-CN surface was observed.

Adaptation of bacterial natural single guide RNA (tracr-L) for efficient plant genome editing.

A long tracrRNA (tracr-L), which naturally act as single guide RNA, and its truncated version, Δtracr-L, from S. pyogenes, efficiently induce Cas9-mediated double-strand breaks (DSBs) in plant genomic loci, as demonstrated by in vitro cleavage assay and protoplast transfection. CRISPR-Cas system provides a form of immune memory in prokaryotes and archaea, protecting them against viruses and foreign genetic elements.

Sialic Acid-Targeted Ru(II)/Ir(III)/Re(I) Complexes for Ferroptosis Induction in Triple-Negative Breast Cancer.

Ferroptosis has been recognized as an iron-based nonapoptotic-regulated cell death process. In the quest of resisting the unyielding vehemence of triple-negative breast cancer (TNBC), herein we have showcased the ferroptosis-inducing heteroleptic [], [], and [] complexes, enabling them to selectively target "sialic acid", an overexpressed cancer cell-surface marker. The open-circuit potential (OCP) measurements in live cancer cells revealed the specific interaction between TNBC and the complexes, whereas control experiments with normal cells did not exhibit such interactions.