Exploring the link between serum uric acid and colorectal cancer: Insights from genetic evidence and observational data.

Colorectal cancer (CRC) is a major cause of cancer-related mortality worldwide. Urate, known for its antioxidant properties, may influence CRC risk and prognosis, but research on this is limited. We used Mendelian randomization (MR) analysis to explore the causal relationship between serum urate levels and CRC risk.

Stigmasterol from Prunella vulgaris L. Alleviates LPS-induced mammary gland injury by inhibiting inflammation and ferroptosis.

Background: Dairy mastitis, a prevalent condition affecting dairy cattle, represents a significant challenge to both animal welfare and the quality of dairy products. However, current treatment options remain limited. Stigmasterol (ST) is a bioactive component of Prunella vulgaris L.

The economic inequality effect of environmental policies--a case from China's "authoritarian environmentalism" actions.

Command-and-control environmental policies are crucial for achieving sustainable development across environmental, economic, and social dimensions. However, these policies often neglect the impact on vulnerable populations and impoverished regions. This paper reveals the mechanisms and impacts of CAC exacerbating regional economic inequality under resource endowment differences through empirical analysis of county panel data in China from 2010 to 2021.

Predicting delayed neurological sequelae in patients with carbon monoxide poisoning using machine learning models.

Introduction: Delayed neurological sequelae is a common complication following carbon monoxide poisoning, which significantly affects the quality of life of patients with the condition. We aimed to develop a machine learning-based prediction model to predict the frequency of delayed neurological sequelae in patients with carbon monoxide poisoning.

Methods: A single-center retrospective analysis was conducted in an emergency department from January 01, 2018, to December 31, 2023.