Quantitative analysis of Δ- and Δ-tetrahydrocannabinol metabolites and isomers: a rapid assay in urine by LC-MS/MS.

An increasing number of cannabis-related products have become available and entered the market, particularly those containing cannabidiol (CBD) and Δ-tetrahydrocannabinol (Δ-THC). Analytical methods for cannabinoids in urine have been described extensively in the literature. However, methods providing good resolution for distinguishing interferences from THC positional isomers are needed.

2-year results from an observational study of proactive treatment regimens with intravitreal aflibercept 2 mg in patients with nAMD in clinical practice: XTEND study UK cohort.

Objectives: The 36-month XTEND (NCT03939767) multicentre, observational, prospective study examined the effectiveness of proactive treatment regimens of intravitreal aflibercept (IVT-AFL) 2 mg in treatment-naïve patients with neovascular age-related macular degeneration (nAMD) in routine clinical practice. The 12- and 24-month outcomes from the XTEND UK cohort are reported.

Methods: Patients aged ≥50 years with nAMD planned to receive IVT-AFL 2 mg were eligible.

Influence of curing regimes on strength development of slag-waste glass-based binary geopolymer.

The disposal of waste glass is an environmental concern to municipal solid waste management authorities. An effective approach for reducing the environmental burdened and disposal problems with waste glass is its reuse in the construction industry. Hence, the feasible utilization of glass powder (GP) was assessed by studying the strength properties of the slag-GP binary geopolymers cured at different curing regimens.

Evaluating accuracy of cervical spine computed tomography interpretation by emergency trainees with the use of a structured protocol.

Objective: Radiological evaluation of cervical spine injury with computed tomography (CT) scanning is a fundamental component of the assessment of major trauma. Accurate interpretation of scans is essential for safe clearance or diagnosis of injuries. However, delays in radiologist reporting often result in prolonged spinal immobilisation.

Mixed evidence for the relationship between HIV stigma and Pain in two studies of people with HIV in Florida.

Previous work suggests that HIV stigma is associated with greater pain severity. We sought to characterize this relationship by examining intersectional identities that tend to be stigmatized (i.e.