Publications by authors named "D P Polyakov"

Article Synopsis
  • A study aimed to evaluate mortality risks in patients with chronic heart failure (CHF) following hospitalization for acute decompensated heart failure (ADHF) over five years, comparing specialized care to general care.
  • It involved 942 patients divided into two groups: one receiving outpatient follow-up at a specialized center and the other at local clinics, with mortality rates analyzed based on various causes.
  • Results showed that specialized follow-up significantly reduced all-cause death (32.3% vs. 53.5%), cardiovascular death, and death from recurrent ADHF risks compared to general follow-up, indicating better outcomes with specialized care.
View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to identify why patients with chronic heart failure (CHF) in Russia have a poor prognosis, using data from various population samples and medical records over several years.
  • It established the prevalence of CHF in the Russian population, finding that 8.2% of individuals meet soft criteria for CHF, while 3.1% met strict criteria, with significant influences from conditions like hypertension and ischemic heart disease.
  • The prognosis for these patients is grim, with over half dying within four years after acute decompensated heart failure (ADHF), and most patients with severe CHF not surviving beyond ten years, primarily due to inadequate medication use and poor patient follow-up.
View Article and Find Full Text PDF

Alpha-synuclein is a protein, the conformational changes of which lead to the development of such socially significant diseases as Parkinson's disease and amyotrophic lateral sclerosis. The methods for differential diagnostics of these diseases based on the use of alpha-synuclein in a non-native conformation obtained from patients as a seed for inducing fibrillogenesis and studying the morphology of the resulting amyloid-like fibrils were described in a number of studies. The authors associate such properties of the seed with the presence of post-translational modifications in the protein obtained from patients.

View Article and Find Full Text PDF

Background: Cystic fibrosis (CF) is a severe hereditary disease with a multisystem lesion. Manifestations of CF include severe infectious purulent lesions of all parts of the respiratory tract, including purulent rhinosinusitis with nasal polyps. The involvement of the sinonasal region and the need for systemic use of ototoxic drugs (primarily aminoglycosides to treat resistant bacterial infection) potentially create a risk of both conductive and sensorineural hearing loss (SNHL).

View Article and Find Full Text PDF

This research is aimed at analyzing existing plugging compositions and developing a new plugging composition based on phenol-formaldehyde resin. This paper presents the results of studies of a hardening composition based on phenol-formaldehyde resin for repair and insulation work in wells. The plugging composition consists of two parts: Component "A" (resin and additives) and Component "B" (hardener).

View Article and Find Full Text PDF