Publications by authors named "D P L Uchoa"
Unlocking breast cancer in Brazilian public health system: Using tissue microarray for accurate immunohistochemical evaluation with limitations in subtyping.
Womens Health (Lond)
January 2025
Background: Breast cancer (BC) is a significant burden on healthcare systems, especially in low- and middle-income countries where access to diagnosis and treatment is challenging.
Objectives: The purpose of this study was to assess the diagnostic accuracy and cost using tissue microarray (TMA) instead of traditional immunohistochemical (IHC) evaluation for estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor 2 (HER2), and the proliferation marker Ki-67 and BC subtyping within the Brazilian public health system.
Design: This is a retrospective cohort study comparing TMA slides with traditional whole-slide evaluation for IHC markers in 242 BC cases.
Oral squamous cell carcinoma arising from areas of Graft-versus-host disease: A systematic review.
Med Oral Patol Oral Cir Bucal
January 2024
Article Synopsis
- Graft-versus-host disease (GVHD) occurs in stem cell transplant patients when donor cells attack the recipient's tissues, leading to complications like oral squamous cell carcinoma (OSCC).
- A systematic review analyzed 23 articles with 81 cases, finding that most patients had myeloid leukemia, with a majority being males around 39 years old, and the tongue was the most common site of GVHD transformation to OSCC.
- OSCCs from GVHD show unique characteristics such as affecting younger individuals, with smoking and alcohol not being significant risk factors, and they generally have a better prognosis, although more research is needed to validate these observations.
Development of a phosphorous-based biorefinery process for producing lignocellulosic functional materials from coconut wastes.
Int J Biol Macromol
June 2023
This work aimed to develop a phosphorous-based biorefinery process for obtaining phosphorylated lignocellulosic fractions in a one-pot protocol from coconut fiber. Natural coconut fiber (NCF) was mixed with 85 % m/m HPO at 70 °C for 1 h to yield the modified coconut fiber (MCF), aqueous phase (AP), and coconut fiber lignin (CFL). MCF was characterized by its TAPPI, FTIR, SEM, EDX, TGA, WCA, and P content.
View Article and Find Full Text PDFThe aim of this study is to report an original case series of synchronous jawbone diseases. Data of patients seen over 13 years were extracted from the files of three Oral Radiology and Pathology diagnostic centers in Brazil. The clinical, radiographic, and laboratory characteristics were tabulated and analyzed by the authors; the patients were described according to lesion type.
View Article and Find Full Text PDFCandida albicans is the most frequently isolated opportunistic pathogen in the female genital tract, with 92.3% of cases in Brazil associated with vulvovaginal candidiasis (VVC). Linalool is a monoterpene compound from plants of the genera Cinnamomum, Coriandrum, Lavandula, and Citrus that has demonstrated a fungicidal effect on strains of Candida spp.
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