Publications by authors named "D P Croft"

Unnecessary antibiotic use is a major driver of antimicrobial resistance, an urgent public health threat. There is an unmet need for improved diagnostics for identifying bacterial etiology in acute respiratory infection (ARI). Hospitalized adults with ARI underwent comprehensive microbiologic testing and those with definitive viral (n = 280), bacterial (n = 129), or mixed viral-bacterial infection (n = 95) had whole blood RNA sequencing.

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Introduction: The Jada System is an FDA-cleared vacuum-induced hemorrhage-control device for the control and treatment of abnormal postpartum uterine bleeding or hemorrhage when conservative management is warranted. The instructions for use for Jada contain a warning stating that the safety and effectiveness of the Jada System in delivery at a gestational age less than 34 weeks or, if multiples, uterus judged less than 34 weeks size, have not been established. While the primary analysis of the RUBY registry, an 800 subject post-approval RWE study of the usage of Jada, included 50 individuals who had preterm births less than 34 weeks gestational age (wGA), the safety and outcomes were not evaluated specifically for less than 28 wGA and 28 to less than 34 wGA subgroups.

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Article Synopsis
  • The study analyzed the relationship between certain types of particulate matter (PM) and hospitalizations or emergency visits for asthma and COPD in New York before and after implementing stricter automobile emission controls.
  • Using statistical methods, it identified that increases in specific PM sources like spark-ignition emissions and secondary sulfates were linked to higher rates of asthma emergency visits, while diesel emissions had a negative association.
  • After the new emission regulations were put in place, there was a decrease in COPD hospital admissions related to some PM sources, but asthma visits generally increased, highlighting the need for further investigation into these trends.
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Article Synopsis
  • Previous studies found a link between higher levels of specific types of particulate matter (PM) and increased cardiovascular hospitalizations in New York, even though overall PM levels dropped.
  • This study used STEMI patient data from the University of Rochester to analyze the effects of various PM types, particularly organic carbon, on heart attack rates from 2014 to 2019.
  • The results indicated that while certain traffic-related PM levels did not correlate with STEMI rates during the later years, higher secondary organic carbon levels might still be linked to an increased risk of heart attacks, especially when looking at data from the early period of the study.
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