Publications by authors named "D P Cardozo Sosa"

Previous evolutionary models of duplicate gene evolution have overlooked the pivotal role of genome architecture. Here, we show that proximity-based regulatory recruitment by distally duplicated genes is an efficient mechanism for modulating tissue-specific production of preexisting proteins. By leveraging genomic asymmetries, we performed a coexpression analysis on tissue data to show the generality of enhancer capture-divergence (ECD) as a significant evolutionary driver of asymmetric, distally duplicated genes.

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Article Synopsis
  • The incorporation of selenocysteine (Sec) into the genetic code has led to the creation of a specialized group of proteins, known as the selenoproteome, across all life forms.* -
  • In humans, the enzyme O-phosphoseryl-tRNASec selenium transferase (SepSecS) has a unique structure that limits its ability to bind more than two tRNASec molecules, due to a specific acidic α-helical extension.* -
  • Research finds that the tRNA-binding mechanisms of SepSecS vary across species, with significant differences between mammals and archaea, indicating that the ability to regulate selenoprotein synthesis has evolved differently in these groups.*
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Fusarium wilt of Banana (FWB) caused by f. sp. (Foc) poses a significant threat to the banana industry, with current inadequate control measures.

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Duckweed ( L.) is a small floating aquatic plant that has an important economic impact in several industrial areas. With its high biomass production, reasonable protein content, and resilience to several climates, it has been attracting increasing interest for potential use in animal and human food systems.

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Background: Chromosomal abnormalities are present in 50 to 60% of miscarriages and in 6 to 19% of stillbirths. Although microarrays are preferred for studying chromosomal abnormalities, many hospitals cannot offer this methodology.

Objective: To present the results of the cytogenetic analysis of 303 products of conception (POC), which included 184 miscarriages, 49 stillbirths and 17 cases of undefined age.

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