This article focuses on current concepts of ischemic heart disease, its interventional treatment, pathomorphology of early and late postoperative complications, and forensic aspects in evaluation of restenosis of a stented blood vessel.
View Article and Find Full Text PDFThe combination of inherited and acquired factors of increased thrombosis complicates establishing the cause-effect relationships between mechanical injury and death during forensic medical examination. Morphometric parameters of the lung tissue and pulmonary vessels in isolated mechanical trauma under conditions of moderate hyperhomocysteinemia were studied in an experiment on laboratory animals. A regularity in changes of the morphometry parameters of the pulmonary vessels was found.
View Article and Find Full Text PDFA model of moderate hyperhomocysteinemia associated with mechanical injury of the musculoskeletal system was developed and experimentally substantiated. The adequacy of this model for studies of morphological and functional regularities is verified. This model can be used for the development of a new concept of evaluation of thrombotic complications of mechanical injury.
View Article and Find Full Text PDFThe objective of the present work was to develop the forensic medical criteria for the assessment of the significance of hereditary predisposition to thrombophilia in the case of thrombotic complications of a mechanical injury. The results of analysis of the frequency of genes responsible for hereditary predisposition to thrombogenesis (FII, FV, MTHFR, FGB, PAL-1) among the victims of mechanical injuries are presented. A total of 251 subjects were available for the examination.
View Article and Find Full Text PDFStatistical data on the incidence and spectrum of thrombotic complications presented in this paper are based on the materials collected by the Department of Expertise of Living Subjects, Rostov Regional Bureau of Forensic Medical Expertise, during 2004-2010. The cases of interest were analysed by age, sex, time of injury, character of traumatic impact, and time of surgical intervention. It is concluded that such cases require forensic medical expertise by standardized methods.
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