Serum level of lactadherin (MFGE8) in inflamatory bowel disease.

Objective: Evaluation of serum lactadherin level, its correlation with disease activity and certain biochemical parameters in IBD patients.

Methods: The study involved adult IBD patients, comprising 50 with ulcerative colitis (UC), 68 with Crohn's disease (CD), and 29 healthy controls.

Results: The MFGE8 median concentration was significantly higher in UC versus controls (1914.

Evaluation of serum levels of soluble (s)L- and (s)P-selectins in endometrial cancer.

Objectives: A number of reports on the role of selectin in the process of carcinogenesis, at the stage of proliferation and metastasis, have been available. The aim of the study was to analyze (s)P- and (s)L-selectin serum concentrations in women with EC and to compare these concentrations to clinical/pathological parameters and disease progression using surgical-pathological staging data.

Material And Methods: A total of 46 patients with EC and 50 healthy controls were included in the study.

Predictive Biomarkers of Pathological Response to Neoadjuvant Chemoradiotherapy for Locally Advanced Soft Tissue Sarcomas.

Background: Marginally resectable and unresectable soft tissue sarcomas (STS) remain a therapy challenge due to the lack of highly active treatment. The aim of the study was to identify a biomarker to predict the pathological response (PR) to preplanned treatment of these STSs.

Methods: In the phase II clinical trial (NCT03651375), locally advanced STS patients received preoperative treatment with a combination of doxorubicin-ifosfamide chemotherapy and 5 × 5 Gy radiotherapy.

The variables in the rationing of nursing care in cardiology departments.

Background: The rationing of nursing care is a complex process that affects the quality of medical services.

Purpose: An assessment of the impact of nursing care rationing on burnout and life satisfaction in cardiology departments.

Methods: The study included 217 nurses working in the cardiology department.

Short-chain fatty acids in the saliva of patients with gastroesophageal reflux disease.

Gastroesophageal reflux disease (GERD) is a condition characterized by persistent symptoms and complications resulting from reflux of gastric contents into the esophagus. Short-chain fatty acids (SCFAs) are fermentation products of dietary fibres by the gut microbiota and are often studied for their anti-inflammatory and anticancer effects. The presence of SCFAs in the upper gastrointestinal tract, including in patients with GERD, has not been previously studied.