Therapeutic considerations in the management of melanoma.

The utilization of Breslow-Clark microstaging has proved helpful in deciding whether or not to perform elective regional node dissection for patients with melanoma. The marked biologic diversity of the disease, however, mandates a strict therapeutic policy of individualization with respect to prognostic variables and special clinical presentation. Specifically, melanomas associated with ulcerations, truncal location, and regional node involvement appear to be more aggressive.

Liver scanning in cancer patients with short-interval autopsy correlation.

The correlation between radionuclide liver scan interpretation and autopsy findings in 94 patients is presented. All patients had a known primary malignancy and the postmortem examinations were performed within 28 days of the scan. In 81% of the cases, the scans were correctly interpreted.

Giant ureteral calculi.

Giant ureteral calculi are defined as weighing at least 50 g or measuring more than 5 cm in greatest diameter. Two patients with this rare entity are described.

Fibrosarcoma of breast metastatic to stomach.

A case of fibrosarcoma of the breast metastatic to the stomach and small bowel is reported. Upper gastrointestinal bleeding secondary to a "bull's eye" or "target" gastric ulcer was successfully treated by surgical resection.