Changing contexts: A quasi-experiment examining adolescent delinquency and the transition to high school.

In a quasi-experiment, we examine whether changing schools during the transition from 8th to 9th grade influences adolescent delinquency, using a sample of more than 14,000 students in 26 public school districts (PROSPER study). The dataset follows students for eight waves from 6th through 12th grade and facilitates a unique, direct comparison of students who change schools with those who remain in the same school during this period. Results show that students who transition between schools report significantly less delinquency after the shift than those who do not, and that this difference persists through 10th grade.

Clinical Validation of Companion Diagnostics for the Selection of Patients with Non-Small Cell Lung Cancer Tumors Harboring Epidermal Growth Factor Receptor Exon 20 Insertion Mutations for Treatment with Amivantamab.

Amivantamab, an epidermal growth factor receptor (EGFR)-c-Met bispecific antibody, targets activating/resistance EGFR mutations and MET mutations/amplifications. In the ongoing CHRYSALIS study (ClinicalTrials.gov Identifier: NCT02609776), amivantamab demonstrated antitumor activity in patients with non-small cell lung cancer harboring EGFR exon 20 insertion mutations (ex20ins) that progressed on or after platinum-based chemotherapy, a population in which amivantamab use has been approved by the US Food and Drug Administration.

Similarity of friends versus nonfriends in adolescence: Developmental patterns and ecological influences.

This study examines developmental change across adolescence in the similarity of friends versus nonfriends. This differential in similarity is a key aspect of the organization of the peer context of development: The stronger the correlation between friends for an attribute, the more the attribute delineates clustering and divisions of friendships. We investigated change in the correlation between friends across 12 attributes covering demographics, orientations to key institutions (family, school, religion), and problem behavior, and we expected that the link between similarity and friendship would increase during adolescence for most attributes other than gender.

Why predict climate hazards if we need to understand impacts? Putting humans back into the drought equation.

Virtually all climate monitoring and forecasting efforts concentrate on hazards rather than on impacts, while the latter are a priority for planning emergency activities and for the evaluation of mitigation strategies. Effective disaster risk management strategies need to consider the prevailing "human terrain" to predict who is at risk and how communities will be affected. There has been little effort to align the spatiotemporal granularity of socioeconomic assessments with the granularity of weather or climate monitoring.

Peer Influence, Friend Selection, and Gender: How Network Processes Shape Adolescent Smoking, Drinking, And Delinquency.

We examine gender differences in the extent to which the social network processes of peer influence and friend selection explain why adolescents tend to exhibit similar risky behaviors as their friends for three problem behaviors (smoking, drinking, and delinquency). Using dynamic Stochastic Actor-Oriented Models (SAOMs), we analyze five waves of data on a large sample of 13,214 adolescents from 51 friendship networks. While both processes explain patterns of risky activities for girls and boys, the delinquent behavior of girls is more susceptible to influence and girls are especially likely to select friends who have similar smoking behaviors to their own.