Publications by authors named "D Orion"
Article Synopsis
- The study focused on improving the diagnosis of clot sources in acute ischemic stroke, particularly distinguishing between atrial fibrillation (AF) and atherosclerosis (AS).
- A new column-based assay for thrombin secretion was developed, which proved to be faster and more informative than previous methods.
- The assay demonstrated high sensitivity and specificity, correctly identifying a significant percentage of patients with AF, thereby enhancing the understanding of cryptogenic strokes and their potential causes.
Genetic workup is becoming increasingly common in the clinical assessment of neurological disorders. We evaluated its yield among middle-aged and elderly neurological patients, in a real-world context. This retrospective study included 368 consecutive Israeli patients aged 50 years and older (202 [54.
View Article and Find Full Text PDFBackground: Information regarding the safety and efficacy of specific direct oral anticoagulants (DOAC) in the treatment of cerebral sinus and venous thrombosis (CSVT) is scarce. Apixaban is one of the most frequently prescribed DOACs. Therefore, we aimed to compare the safety and efficacy of Apixaban with those of vitamin k antagonists (VKA) in patients with CSVT.
View Article and Find Full Text PDFBackground: Levetiracetam is widely used in post-stroke epilepsy. However, it is suspected to possess P-glycoprotein (P-gp) induction properties, and therefore, a potentially significant interaction with direct oral anticoagulants (DOACs). We aimed to search for ischemic stroke signals with levetiracetam and the DOACs.
View Article and Find Full Text PDFArticle Synopsis
- * Researchers measured thrombin activity in blood clots washed during stroke treatment, finding that changes in thrombin levels could indicate where the clot originated.
- * The study suggests that the difference in thrombin levels is linked to the clot's location, with higher blood flow areas washing out thrombin, while lower flow areas retain it.