APPROACH: Analysis of Proton versus Photon Radiotherapy in Oligodendroglioma and Assessment of Cognitive Health - study protocol paper for a phase III multicentre, open-label randomised controlled trial.

Introduction: Oligodendroglioma (ODG) is a rare type of brain tumour, typically diagnosed in younger adults and associated with prolonged survival following treatment. The current standard of care is maximal safe debulking surgery, radiotherapy (RT) and adjuvant procarbazine, lomustine and vincristine (PCV) chemotherapy. Patients may experience long-term treatment-related toxicities, with RT linked to impairments of neurocognitive function (NCF) and health-related quality of life (HRQoL).

Spatial, environmental and trophic niche partitioning by seabirds in a climate change hotspot.

For similar species to co-occur in places where resources are limited, they need to adopt strategies that partition resources to reduce competition. Our understanding of the mechanisms behind resource partitioning among sympatric marine predators is evolving, but we lack a clear understanding of how environmental change is impacting these dynamics. We investigated spatial and trophic resource partitioning among three sympatric seabirds with contrasting biological characteristics: greater crested terns Thalasseus bergii (efficient flyer, limited diver, and preference for high quality forage fish), little penguins Eudyptula minor (flightless, efficient diver, and preference for high quality forage fish) and silver gulls Chroicocephalus novaehollandiae (efficient flyer, limited diver and generalist diet).

Association of 24-h movement behaviors during Covid-19 pandemic with spinal musculoskeletal disorders in undergraduate students: a cross-sectional study.

Background And Aims: Musculoskeletal disorders (MSD) are an important health problem, and the Covid-19 pandemic affected several lifestyle and health aspects worldwide, including moderate-to-vigorous physical activity (MVPA), sedentary behavior (SB) and sleep time, which compose the 24-h movement guidelines (24-hMG). It is unclear whether meeting 24-hMG during pandemic have been associated with MSD in adult population and this study aimed to analyze the association of meeting 24-hMG with spinal MSD in undergraduate students during Covid-19 pandemic.

Methods: A sample of 71 undergraduate students were assessed (24.

Rate of decline in kidney function with age: a systematic review.

Objective: To determine the distribution of kidney function values as measured by glomerular filtration rate (GFR), and the rate of decline with age in male and female healthy subjects without pre-existing medical conditions.

Design: Systematic review and structured synthesis.

Search Sources: PubMed, Embase, Cochrane Central Register of Controlled Trials and Web of Science, from database inception to 25 October 2023.