Publications by authors named "D Obata"
Article Synopsis
- Researchers studied apolipoprotein A2-isoforms (apoA2-is) as potential biomarkers for early-stage pancreatic cancer and developed a new diagnostic assay for them.
- The study included 2732 plasma samples and showed that apoA2-ATQ/AT has a higher ability to distinguish pancreatic cancer from healthy controls compared to the traditional biomarker CA19-9.
- ApoA2-ATQ/AT also demonstrated better sensitivity for detecting early-stage pancreatic cancers, and using it in combination with CA19-9 boosted detection rates significantly.
Article Synopsis
- Researchers studied factors linked to overlapping symptoms of functional dyspepsia (FD) and nonerosive reflux disease (NERD) in 3,085 Japanese individuals who underwent endoscopy.
- Among participants, 2.4% had FD alone, 3.1% had NERD alone, and 2.7% experienced the overlap of both conditions.
- Key factors for this overlap included being female, having a low body mass index, significant alcohol consumption, and higher anxiety levels.
Article Synopsis
- The study investigates the long-term outcomes of endoscopic submucosal dissection (ESD) for early remnant gastric cancer (ERGC) using a large multicenter database, addressing a gap in previous research that focused on single centers.
- A total of 242 cases were analyzed, with a median follow-up of 48.4 months, revealing a 5-year overall survival rate of 81.3% and a gastric cancer-specific survival rate of 98.1%.
- The results indicate that while ESD is effective for ERGC regardless of hospital volume, patients categorized as endoscopic curability C-2 without further surgery had significantly shorter survival compared to those with higher curability ratings or those who underwent additional
The Mg-dechelatase enzyme encoded by the () gene catalyzes Mg dechelation from chlorophyll This reaction is the first committed step of chlorophyll degradation pathway in plants and is thus indispensable for the process of leaf senescence. There is no structural information available for this or its related enzymes. This study aims to provide insights into the structure and reaction mechanism of the enzyme through biochemical and computational analysis of an SGR homolog from the Chloroflexi (AbSGR-h).
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