Immunodetection of Poorly Soluble Substances: Limitations and Their Overcoming.

Immunoassays based on the specific antigen-antibody interactions are efficient tools to detect various compounds and estimate their content. Usually, these assays are implemented in water-saline media with composition close to physiological conditions. However, many substances are insoluble or cannot be molecularly dispersed in such media, which objectively creates problems when interacting in aquatic environments.

Circulating microRNAs as Non-Invasive Biomarkers in Endometriosis Diagnosis-A Systematic Review.

The aim of this systematic review is to assess the power of circulating miRNAs as biomarkers as a diagnostic tool in endometriosis. In endometriosis-suspected women with uncertain imaging, the only way to confirm or exclude endometriosis with certainty is currently laparoscopy. This creates a need for non-invasive diagnostics.

[Accessibility barriers to primary care in a Pernambuco, Brazil, settlement via the perspective of peasants, health professionals, and management].

We are unable to deny the iniquities which are directly involved in the ways of being born, living, falling ill, and dying of the rural population. To analyze these people's accessibility to health care, we considered four barriers pertinent to accessibility to primary care: geography, organization, finance, and information. This study stresses the accessibility barriers to primary care which the population of a Pernambuco, Brazil, settlement faces from the perspective of settlers, professionals, and management.

Cultural Adaptation and Validity Testing of the Portuguese Version of the Health Literacy Questionnaire (HLQ).

Background: Health literacy is considered a determinant of self-management behaviors and health outcomes among people with diabetes. The assessment of health literacy is central to understanding the health needs of a population. This study aimed to adapt the Health Literacy Questionnaire (HLQ) to the Portuguese context and to examine the psychometric properties of a population of people with diabetes.