Publications by authors named "D Nurjadi"

Article Synopsis
  • - Cefiderocol is a new antibiotic effective against multidrug-resistant pathogens, showing potential against carbapenem-resistant Pseudomonas aeruginosa (Cr-Pa) infections based on a study of 108 isolates.
  • - Out of these isolates, nine displayed resistance with specific mutations linked to iron uptake systems and other resistance-related genes, while no correlation was found between carbapenemases and cefiderocol resistance.
  • - The study indicates that while cefiderocol remains a viable treatment option, ongoing research is needed to understand the evolving resistance mechanisms and enhance strategies for managing antimicrobial resistance.
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Article Synopsis
  • - The rise of autochthonous tropical diseases in Europe is tied to climate change, which is affecting the distribution and activity of disease-carrying vectors like mosquitoes and ticks.
  • - Notable species like Aedes albopictus and Aedes aegypti have created stable populations in Europe, leading to increased cases of diseases such as dengue fever and West Nile virus in previously unaffected temperate areas.
  • - To combat these emerging health threats, experts recommend enhancing disease surveillance, developing weather-related predictive models, and improving vector control strategies to safeguard public health against the effects of climate change.
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Purpose: Since winter 2022, invasive GAS (iGAS) infections have re-emerged in Europe, causing severe diseases in children and adults. We aimed to examine whether this reported post-pandemic increase was associated with an increased disease severity and/or a shift in clinical disease phenotypes.

Methods: We performed detailed clinical phenotyping of patients hospitalized with iGAS infections at a 1410-bed tertiary German Medical Center from 01/2015 to 09/2023.

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Article Synopsis
  • * A study in Vietnam involving 330 patients compared the BioFire FilmArray Meningitis/Encephalitis (FAME) Panel to traditional diagnostic methods, with FAME showing an 87% agreement rate and detecting 19% of specimens.
  • * While FAME offers rapid pathogen detection, it's not a complete replacement for traditional methods and should be tailored to local disease patterns to improve healthcare outcomes.
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