Application of a simple copper(II) complex compound as an epinephrine selective voltammetric sensor in the presence of uric acid under aqueous conditions.

Developing sensors with high sensitivity and selectivity for detecting neurotransmitters under near-physiological conditions is a major challenge and is crucial for preventing diseases of the nervous, cardiovascular, and endocrine systems. Most existing systems that meet these requirements involve either complicated synthesis processes, require sulfur groups, or are not functional under aqueous conditions. Herein, we report that the self-organisation of a simple imine ligand L with copper(II) tetrafluoroborate leads to the formation of a [CuL](BF) complex (CuL) with a 2 : 1 ligand-to-metal ratio, as confirmed by high-resolution electrospray ionization mass spectrometry (HR ESI-MS), Fourier-transform infrared (FT-IR) spectroscopy and single-crystal X-ray analysis.

The effect of ionic covalent functionalization of polyoxometalate hybrid materials with coordinating subunits on their stability and interaction with DNA.

Inorganic-organic hybrid materials that combine both Polyoxometalates (POMs) and metal ion coordinating subunits (CSUs) represent promising multifunctional materials. Though their individual components are often biologically active, utilization of hybrid materials in bioassays significantly depends on the functionalization method and thus resulting stability of the system. Quite intriguingly, these aspects were very scarcely studied in hybrid materials based on the Wells-Dawson POM (WD POM) scaffold and remain unknown.

Enhancing Quality of Life and Sexual Functioning in Female Androgenetic Alopecia: Therapeutic Potential of Hair Follicle-Derived Stem Cells.

Background: The study aimed to examine the impact of stem cell treatment on quality of life (QoL) and sexual functioning in women with androgenetic alopecia (AGA).

Methods: Twenty-three women underwent a single session of autologous cellular micrografts (ACMs). The World Health Organization Quality of Life Brief Version (WHOQOL-BREF) and Female Sexual Function Index (FSFI) were used before and after 6 months.

Five decades of the use of botulinum toxin in ophthalmology.

Botulinum toxin (BoNT) has been known for over 50 years. It has conquered many areas of medicine and has become indispensable in contemporary medicine. Now, BoNT is used to treat at least 26 conditions in six medical specialties.