Publications by authors named "D Njoku"

Article Synopsis
  • * This study focuses on the biosynthesis of rare MIAs in the Tabernaemontana litoralis plant, identifying new CYP enzymes that specifically modify MIA structures, including the discovery of a new MIA compound.
  • * The research enhances our understanding of how MIAs are synthesized and diversified in T. litoralis, suggesting its potential for future studies in this area.
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Article Synopsis
  • Aluminum alloys are popular for their high strength-to-weight ratio, achieved through alloying elements and heat treatments that create intermetallic particles (IMPs) which affect their corrosion resistance.
  • The review focuses on the electrochemical and galvanic corrosion behaviors of various important intermetallic compounds commonly found in aluminum alloys, detailing specific phases like Q-phase, π-phase, and θ-phase.
  • It also addresses limitations in studying these compounds, identifies research gaps, and discusses phenomena such as galvanic polarity reversal and the self-dissolution of IMPs.
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Monoterpenoid indole alkaloids (MIA) are one of the largest and most complex alkaloid class in nature, boasting many clinically significant drugs such as anticancer vinblastine and antiarrhythmic ajmaline. Many MIAs undergo nitrogen -methylation, altering their reactivity and affinity to the biological targets through a straightforward reaction. Remarkably, all known MIA -methyltransferases (NMT) originate from the neofunctionalization of ancestral γ-tocopherol -methyltransferases (γTMTs), a phenomenon seemingly unique to the Apocynaceae family.

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Nitrogen (N) is an important nutrient element needed by cassava for optimum yield and it is a vital component of nucleotides (nucleic acids), enzymes, amino acids (proteins), chlorophyll molecules and hormones, among other essential compounds required for growth and development of cassava. Nitrogen stress is a major cassava production constraint, the study aimed to examine genotype by environment interaction (GEI) effects and fresh root yield stability of 203 diverse cassava clones to identify genotypes with stable performance under low and optimum nitrogen regimes across environments using AMMI and GGE biplot analysis. Experiments were conducted using an augmented block design with three replications for two years in three locations in Nigeria.

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