Chronic wounds, defined by their prolonged healing process, significantly impair patient quality of life and impose a hefty financial burden on healthcare systems worldwide. Sex/gender-specific mechanisms regulate inflammation and infection, angiogenesis, matrix synthesis, and cell recruitment contribute to cutaneous wound healing, but remain largely understudied. This review is aimed to spotlight the innovative realm of bioengineering and nanomedicine, which is at the helm of revolutionizing complex chronic wound care.
View Article and Find Full Text PDFAdditive manufacturing is an expanding multidisciplinary field encompassing applications including medical devices, aerospace components, microfabrication strategies and artificial organs. Among additive manufacturing approaches, light-based printing technologies, including two-photon polymerization, projection micro stereolithography and volumetric printing, have garnered significant attention due to their speed, resolution or potential applications for biofabrication. Here we introduce dynamic interface printing, a new 3D printing approach that leverages an acoustically modulated, constrained air-liquid boundary to rapidly generate centimetre-scale 3D structures within tens of seconds.
View Article and Find Full Text PDFCustomizable manufacturing of ex vivo cell engineering is driven by the need for innovations in the biomedical field and holds substantial potential for addressing current therapeutic challenges; but it is still only in its infancy. Micro- and nanoscale-engineered materials are increasingly used to control core cell-level functions in cellular engineering. By reprogramming or redirecting targeted cells for extremely precise functions, these advanced materials offer new possibilities.
View Article and Find Full Text PDFThe purpose of this study was to evaluate the test-retest reliability of the instrumented version of the modified Clinical Test of Sensory Interaction on Balance (i-mCTSIB) using the VirtuSense VirtuBalance System™ (VSTBalance), a virtual balance device, in healthy young adults. Fifty-four subjects aged 20-27 years (Mean age 23.07, SD ± 1.
View Article and Find Full Text PDF