Creation of a Custom Endoluminal Vacuum-Assisted Device for Salvage of Ileal Pouch-Anal Anastomotic Leak.

Endoluminal vacuum-assisted devices have become increasingly popular solutions for low-colorectal injuries and anastomotic defects in recent years. We present a case of a 23-year-old male who underwent salvage of an ileal pouch-anal anastomosis (IPAA) anastomotic leak with a customized endoluminal vacuum sponge and cavity marsupialization. This case highlights the easy-to-follow steps to create a customized endoluminal vacuum (endo-vac) sponge with readily available materials for the treatment of low colorectal anastomotic leaks.

From public to commercial service: State-market hybridization in the UK visa and immigration permit infrastructure, 1997-2021.

This article charts the transformation, between 1997 and 2021, of the family visa and immigration permit infrastructure from a public into a commercial service in the United Kingdom. In doing so, it reveals a process of state-market hybridization underpinning the commercialization of migration regulation. Drawing on the analysis of legal archives, policy reports, and marketing materials directed at family migrants spanning 1997-2021, it presents fresh, systematic evidence of how, since 2007, a commercialized state-market hybrid migration infrastructure for visas and immigration permits has developed in the UK.

Maltreatment and depression among left-behind adolescents in rural China: The moderating roles of food security and depression literacy.

Background: Maltreatment is a leading cause of adolescent depression. Economic empowerment and mental health services provision are major policy options to solve this problem in developing countries. However, little is known about how these policy options jointly influence the association between maltreatment and adolescent depression.

Mindfulness and the 'psychological imagination'.

We analyse the rise of 'mindfulness' in English language media discourses and contextualise it in terms of its expression of a persistent underlying 'psychological imagination' in contemporary thinking about social problems. An inversion of C. Wright Mills' much-cited sociological imagination, the psychological imagination draws on medical-scientific authority to treat social problems as private concerns rooted in individual biology, mentality and behaviour.

Experimental and modelling study of different process modes for retroviral production in a fixed bed reactor.

Pseudotype vectors are promising for gene transfer in many gene therapy approaches, however, low-vector concentration in batch cultures and high temperature-dependent decay do limit sufficiently large-scale production. To overcome these obstacles, the kinetic relations of cell growth and vector formation in different culture modes need to be understood. Effective optimisation of process modes is needed to achieve sufficient yields.