Immunogenicity of macrophage RNA and its properties.

Date on the ability of ribonucleic acid, extracted from antigenically stimulated macrophages, to transform normal spleen cells into immunocompetent cells are reported, along with some properties of the same ribonucleic acid. It was observed that: 1 - RNA isolated from antigenically stimulated macrophages may transform normal spleen cells into immunocompetent cells.2 - Antibodies formed by these cells belong to the IgM class.

The activity of Newcastle disease virus-envelope proteins after treatment with detergents.

Treatment of NDV with anionic detergents or lipid solvents destroys the activities of hemagglutinin and neuraminidase. After disruption of the virus with non-ionic detergents, the activities of envelope proteins remain unchanged. It is suggested that the phosholipids are very important for the biological activity of NDV-envelope proteins.