Publications by authors named "D N Vergara-Ortega"

Article Synopsis
  • * Young women (ages 18-24) had a higher HSV-2 seroprevalence (12.1%) compared to adolescents (4.3%), with frequent alcohol consumption also linked to a higher risk of infection.
  • * Although vaginal HSV-2 shedding peaked in the third trimester, the difference wasn't statistically significant; nonetheless, this increases the risk of neonatal herpes from vertical transmission during pregnancy.
View Article and Find Full Text PDF
Article Synopsis
  • * Conducted in 2021-2022, the research involved 462 migrants who filled out questionnaires and underwent blood tests to detect these infections, revealing a 29.9% prevalence for HSV-2 and 4.5% for syphilis, particularly higher in men.
  • * The findings show that both infections are highly present among the migrant population, highlighting the need for targeted prevention and treatment efforts, especially considering their unique vulnerabilities related to sexual behavior.
View Article and Find Full Text PDF
Article Synopsis
  • * Study findings identify various risk factors for syphilis among MSM, including low economic status, use of inhalant drugs, and specific sexual practices.
  • * There is a growing need for targeted prevention efforts in Mexico to address both syphilis and HIV among MSM, particularly considering the increasing prevalence observed in more recent years.
View Article and Find Full Text PDF

Syphilis is a sexually transmitted disease that has become a public health problem, especially in vulnerable populations. A systematic review and time-free meta-analysis of the publications on the molecular detection of syphilis and mutations associated with antibiotic resistance, CORE group, and syphilis genotypes in PubMed databases, Scielo, and Cochrane was performed, and the last search was conducted in June 2022. Proportions were calculated, and standard errors and confidence intervals were reported for all results of interest.

View Article and Find Full Text PDF

Much is known about the natural history of syphilis; however, less is known about the immune response against it, and even less is known about people living with HIV (PLWH). Due to the lack of an animal model to study host-pathogen interactions, it remains unclear how the host eliminates the bacteria. Here, we attempt to elucidate the immune response against infection by summarizing all the reported data in a systematic review.

View Article and Find Full Text PDF