Radiographic findings in dogs from an endemic area for heartworm disease in the state of Rio de Janeiro.

Canine heartworm disease causes significant pulmonary abnormalities, even in asymptomatic cases. This study aimed to compare the chest radiographs of cases infected with with those of heartworm-negative dogs. Fifteen animals treated at a private veterinary clinic in the municipality of Maricá, Rio de Janeiro, underwent chest radiography, regardless of their serological status, for the presence of antigen, and none of them used preventive measures.

Development of a Population Pharmacokinetic Model Characterizing the Tissue Distribution of Resveratrol After Administration by Different Routes and Doses in Rats.

Studies have demonstrated that resveratrol exerts several pharmacological effects. However, the pharmacokinetic parameters are not completely established. This study describes the plasma pharmacokinetics and tissue distribution of resveratrol after administration by different routes and doses in rats.

Twenty-four weeks of combined training in different environments, aquatic and land, in the type 2 diabetes management (Aquatic and Land Exercise for Diabetes -ALED): protocol of a randomized clinical trial.

Background: Physical exercise is crucial in type 2 diabetes management (T2D), and training in the aquatic environment seems to be a promising alternative due to its physical properties and metabolic, functional, cardiovascular, and neuromuscular benefits. Research on combined training in aquatic and dry-land training environments is scarce, especially in long-term interventions. Thus, this study aims to investigate the effects of combined training in both environments on health outcomes related to the management of T2D patients.

Correction: Soares, D.J. Bridging a Century-Old Problem: The Pathophysiology and Molecular Mechanisms of HA Filler-Induced Vascular Occlusion (FIVO)-Implications for Therapeutic Interventions. 2022, , 5398.

In the original publication [...

Color Change and Cytotoxic Effects of a Bleaching Gel With 22% Carbamide Peroxide Catalyzed by Manganese Oxide.

Objectives: To evaluate the color change and trans-amelodentinal cytotoxicity of a 22% carbamide peroxide (CP) bleaching gel containing different concentration of manganese oxide (MnO).

Material And Methods: Enamel/dentin discs adapted to artificial pulp chambers were distributed according to treatments: CN-No treatment; CP22%-22%CP; CP22 + 2MnO-22%CP + 2 mg/mLMnO; CP22% + 6MnO-22%CP + 6 mg/mLMnO; CP22% + 10MnO-22%CP + 10 mg/mLMnO applied for 2 h for 15 days. Color change-CC (ΔE and ΔWI) (n = 8) was determined at 5, 10, and 15-day periods (ANOVA/Sidak).