[Effect of a "direct" hemolytic factor and phospholipse A2 from Middle-Asian cobra venom on erythrocytes].

The effect of "direct" hemolytic factor (DHF) and phospholipase A2, isolated and purifed from Middle-Asian cobra venom on human erythrocytes is studied. DHF is found to increase the hemolytic effect of phospholipase A2 Ca2+ ions inhibit the hemolytic effect of DHF, but they increase the hemolysis in the presence of DHF and phospholipse A2. Heparin re moves the increasing effect of DHF.