[The mutation spectrum of the GJB2 gene in Belarussian patients with hearing loss. Results of pilot genetic screening of hearing impairment in newborns].

A total of 111 unrelated probands and their 8 sibs from Grodno oblast (Belarus) with bilateral isolated sensorineural hearing impairment were studied for the presence of mutations in the connexin 26--GJB2gene. Mutations were detected in 51 probands (46% of the sample). A significantly higher frequency of the GJB2gene mutations was observed in familial cases of the disease with the autosomal recessive type of inheritance (in 78% of families).

[Auditory brainstem response (ABR) during stapes mobilization under general anaesthesia in children].

The Authors executed checking a result of stapes mobilization under anesthesia in children, sick otosclerosis. The Study ABR was conducted before operations, after opening the drum cavity, making the hole in plate of stapes, installing the prosthetic device and at the end of operation. The reduction level of latency V wave and interval III-V and I-V waves are a reliable acknowledgement of the improvement of the hearing at the end of operation.