Publications by authors named "D N Makau"

The objective of this study was to evaluate biosecurity practices related to chronic wasting disease (CWD) transmission pathways and prevention in active cervid herds in Minnesota in 2019 by species, size and location of herds. A self-administered questionnaire was sent to all cervid producers in Minnesota to gather demographic, management, and biosecurity practices. Among producers (N=136), 63.

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Porcine epidemic diarrhea (PED) and Porcine reproductive and respiratory syndrome (PRRS) are viral diseases that continue to challenge the US swine industry. Despite many known risk factors, unusual circumstances associated with their occurrence continues to be poorly explained. We investigated if extreme weather events (flood, heavy rain, high wind and tornadoes, measured at a county-level) are associated with the occurrence of both diseases up to ten weeks after the occurrence of the weather event using a case control study and logistic regression modeling to control for covariates.

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New PRRSV variants are constantly emerging due to the rapid evolution of this virus. We aimed to describe the emergence of a new PRRSV variant within sub-lineage 1 C, its space-time distribution, and its impact on affected herds. Additionally, we discuss considerations on how to monitor emerging PRRSV variants.

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The United States (U.S.) swine industry has struggled to control porcine reproductive and respiratory syndrome (PRRS) for decades, yet the causative virus, PRRSV-2, continues to circulate and rapidly diverges into new variants.

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The repeated emergence of new genetic variants of PRRSV-2, the virus that causes porcine reproductive and respiratory syndrome (PRRS), reflects its rapid evolution and the failure of previous control efforts. Understanding spatiotemporal heterogeneity in variant emergence and spread is critical for future outbreak prevention. Here, we investigate how the pace of evolution varies across time and space, identify the origins of sub-lineage emergence, and map the patterns of the inter-regional spread of PRRSV-2 Lineage 1 (L1)-the current dominant lineage in the U.

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