Acta Crystallogr Sect E Struct Rep Online
February 2012
In the title compound, C(14)H(16)N(6)O(6)·C(2)H(6)O·H(2)O, both substit-uents of the benzene ring are approximately planar with maximum deviations from the mean plane of 0.0561 (12) (an imine N atom) and 0.1419 (11) Å (a meth-oxy O atom).
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October 2011
In the title molecule, C(24)H(15)Cl(4)N(3)O(4), the triazole ring makes dihedral angles of 72.02 (12), 81.60 (12) and 73.
View Article and Find Full Text PDFExperiments on various animals showed that dichlotazole, a new triazole derivative, possesses a high antiinflammatory activity and low toxicity. The mechanism of the antiphlogistic effect of dichlotazol is due to its antagonism with respect to mediators of the inflammatory process and the ability of suppressing the increased permeability of capillaries.
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