Publications by authors named "D N Holdren"

Purpose/methods: We evaluated visual field testing, using indirect ophthalmoscopy, in patients with retinal detachment or retinoschisis. While performing ophthalmoscopy, we projected a shadow onto the schisis or detachment by holding a scleral depressor on the observer's side of the condensing lens. A response was recorded as positive if the patient saw the shadow.

View Article and Find Full Text PDF

The question of whether A-bands shorten during contraction was investigated using two methods: high-resolution polarization microscopy and electron microscopy. During shortening from extended sarcomere lengths in the passive state, sarcomere-length changes were essentially accounted for by I-band shortening. During active shortening under otherwise identical conditions, the sarcomere length change was taken up approximately equally by A- and I-bands.

View Article and Find Full Text PDF

The smearing effects due to thermal conduction along various, nonenergized, interstitial devices were quantified in a flow cell-thermal step gradient. An insulated cylindrical flow cell with a high (ca 45 degrees C, 1.12 cm i.

View Article and Find Full Text PDF