In many sensory systems the formation of burst firing can be observed along a way from the periphery to the central nuclei. We investigate the putative transformation of spontaneous activity in the auditory pathway using a neuron model trained by real firing recorded in the auditory nuclei of the frog. The model has 200 separate inputs (neuronal spines).
View Article and Find Full Text PDFThe peritumor-like areas of 12 cerebral hemispheric tumors were examined. Histological study revealed vascular malformations and/or congenital tissue dysplasias in all cases: cortical disorganization, neuronal heterotopy into the white matter, neural location in the molecular cortical layer, and persistence of a subpial granular cell layer. Immunohistochemical study using Ki-67 antibodies in the peritumor-like tissue dysplasias revealed proliferative activity in a number of cases.
View Article and Find Full Text PDFUsing the method of differential scanning calorimetry, the DNA helix-coil transition was studied in solutions (10(-3) M Na+, 10(-3) M tris HCl, pH 7.0) containing divalent copper ions at relative metal ion concentrations (Mt2+/PDNA) ranging from 0.2 to 20.
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