Balancing agriculture and environment: Andrew Sharpley's nutrient, soil, and water management legacy.

Managing agricultural phosphorus (P) to balance food security and water quality priorities is a massive challenge fraught with uncertainty and competing interests. Throughout his career, Andrew Sharpley addressed this challenge by building our understanding of the fundamental principles and processes that control P behavior in agricultural land, developing tools to assess P losses, and then evaluating and refining nutrient, soil, and water beneficial management practices (BMPs). Together with an exceptionally large and diverse group of collaborators, Sharpley developed, tested, refined, calibrated, and validated management practices and risk assessment tools to develop site-specific recommendations for the right practices, in the right places, and at the right times.

Risk of Treatment Failure for Prosthetic Joint Infections: Retrospective Chart Review in an Outpatient Parenteral Antimicrobial Therapy Program.

Background: Prosthetic joint infections (PJIs) are a major complication of total joint replacement surgeries. Treatment includes surgical intervention with prolonged courses of IV antibiotics in outpatient parenteral antimicrobial therapy (OPAT) programs. The risk of PJI treatment failure is high and may be associated with various clinical factors.

4R Management of Phosphorus Fertilizer in the Northern Great Plains.

Phosphorus (P) fertilizer has played a vital role in increasing the productivity of crop production in the northern Great Plains for approximately 100 years. Throughout this period, agricultural production practices have changed dramatically, while our knowledge of P behavior and beneficial management practices has improved. Some of the more recent and substantial changes in farming practices on the northern Great Plains include widespread adoption of reduced tillage systems, introduction of new crops and high-yielding cultivars, intensification and extension of crop rotations, development of new fertilizer products, increased appreciation of the role of microbial interactions in P dynamics, and growing concern for the effects of P on water quality.

Future Phosphorus: Advancing New 2D Phosphorus Allotropes and Growing a Sustainable Bioeconomy.

With more than 40 countries currently proposing to boost their national bioeconomies, there is no better time for a clarion call for a "new" bioeconomy, which, at its core, tackles the current disparities and inequalities in phosphorus (P) availability. Existing biofuel production systems have widened P inequalities and contributed to a linear P economy, impairing water quality and accelerating dependence on P fertilizers manufactured from finite nonrenewable phosphate rock reserves. Here, we explore how the emerging bioeconomy in novel, value-added, bio-based products offers opportunities to rethink our stewardship of P.