Publications by authors named "D N Baron"

Purpose: Oncoplastic breast-conserving surgery (OBCS) prevents compromise of breast aesthetics following large breast cancer excisions. This systematic review was conducted to investigate the outcomes (oncologic, surgical, cosmetic) of OBCS versus standard breast-conserving surgery (SBCS) and mastectomy post-neo-adjuvant systemic therapy.

Methods: Ovid, Web of Science, Cochrane, ClinicalTrials.

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  • The opioid crisis has evolved into a global issue affecting various socioeconomic and cultural areas, with traditional treatment methods proving insufficient.
  • A narrative review was conducted using multiple databases to explore the complex factors contributing to this epidemic, acknowledging the potential for bias in article selection.
  • Despite some progress with Opioid Substitution Therapy, U.S. overdose deaths remain alarmingly high and are projected to increase; the authors suggest a need for a new treatment approach that targets brain neurotransmitter systems for better management.
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  • Borderline personality disorder (BPD) and post-traumatic stress disorder (PTSD) share similar neurobiological features, suggesting that BPD might be better classified as "traumatic personality stress disorder" (TPSD).
  • The study explores how psychedelic-assisted therapy (PAT) could effectively treat both BPD and PTSD, emphasizing its role in stabilizing reward functions.
  • Reclassifying BPD as TPSD may lead to more personalized treatment approaches, reduce stigma, and improve understanding and management of related psychological conditions.
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  • - Reward Deficiency Syndrome (RDS) refers to a range of addictive behaviors affecting many people, prompting research on KB220 and its variants to tackle these issues.
  • - The studies focus on various impacts of KB220, including cravings, substance abuse prevention, and mental health conditions like ADHD and eating disorders.
  • - The review posits that KB220 is more effective than GLP-1 analogs in improving brain functions related to reward and dopamine balance without negatively affecting the reward system.
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