Why men don't talk about domestic violence.

A personal anecdote highlighting the myriad myths and misconceptions about why men don't often report domestic violence and the steps that society can take to ensure that everyone who has experienced such violence gets the resources and support they need.

Grindr? it's a "Blackmailer's goldmine"! The weaponization of queer data publics Amid the US-China trade conflict.

In March 2019, the Committee on Foreign Investment in the United States (CFIUS) identified Grindr, a hookup app that predominantly caters to men who have sex with men, as a "national security threat" and compelled the Chinese conglomerate Kunlun Tech to divest from it entirely. The CFIUS-Grindr ruling is indicative of larger regulatory debates over increasing datafication trends in the dating app industry. Through a political economy approach to communication, this paper examines how this ruling was predominantly constructed by various stakeholders a public controversy in light of the ongoing US-China trade conflict.

Revealing the atomic and electronic mechanism of human manganese superoxide dismutase product inhibition.

Human manganese superoxide dismutase (MnSOD) is a crucial oxidoreductase that maintains the vitality of mitochondria by converting superoxide (O) to molecular oxygen (O) and hydrogen peroxide (HO) with proton-coupled electron transfers (PCETs). Human MnSOD has evolved to be highly product inhibited to limit the formation of HO, a freely diffusible oxidant and signaling molecule. The product-inhibited complex is thought to be composed of a peroxide (O) or hydroperoxide (HO) species bound to Mn ion and formed from an unknown PCET mechanism.

The role of Tyr34 in proton-coupled electron transfer of human manganese superoxide dismutase.

Human manganese superoxide dismutase (MnSOD) plays a crucial role in controlling levels of reactive oxygen species (ROS) by converting superoxide (O ) to molecular oxygen (O) and hydrogen peroxide (HO) with proton-coupled electron transfers (PCETs). The reactivity of human MnSOD is determined by the state of a key catalytic residue, Tyr34, that becomes post-translationally inactivated by nitration in various diseases associated with mitochondrial dysfunction. We previously reported that Tyr34 has an unusual pK due to its proximity to the Mn metal and undergoes cyclic deprotonation and protonation events to promote the electron transfers of MnSOD.

The role of Tyr34 in proton-coupled electron transfer of human manganese superoxide dismutase.

Human manganese superoxide dismutase (MnSOD) plays a crucial role in controlling levels of reactive oxygen species (ROS) by converting superoxide (O ) to molecular oxygen (O ) and hydrogen peroxide (H O ) with proton-coupled electron transfers (PCETs). The reactivity of human MnSOD is determined by the state of a key catalytic residue, Tyr34, that becomes post-translationally inactivated by nitration in various diseases associated with mitochondrial dysfunction. We previously reported that Tyr34 has an unusual pK due to its proximity to the Mn metal and undergoes cyclic deprotonation and protonation events to promote the electron transfers of MnSOD.