Publications by authors named "D Munoz-Valverde"
Article Synopsis
- Oral gavage used in drug studies can cause issues, so voluntary ingestion of gelatin-based supplements in rats presents a better alternative for administration.
- Research found that male rats are less likely to accept the gelatin than females, but fasting improved acceptance for females; additives like vanilla and sucralose did not have an effect.
- The study concluded that trained rats can reliably consume supplements without affecting lactation, making this method useful for administering drugs that need to be digested and ensuring all rats can participate in studies.
Background And Aims: Left ventricular hypertrophy (LVH) in hypertension is associated with a greater risk of sustained supraventricular/atrial arrhythmias. Dronedarone is an antiarrhythmic agent that was recently approved for the treatment of atrial fibrillation. However, its effect on early regression of LVH has not been reported.
View Article and Find Full Text PDFIntrauterine and perinatal life are critical periods for programming of cardiometabolic diseases. However, their relative role remains controversial. We aimed to assess, at weaning, sex-dependent alterations induced by fetal or postnatal nutritional interventions on key organs for metabolic and cardiovascular control.
View Article and Find Full Text PDFObjective: The aim of this work is to analyse the origin of phenotypic plastic changes into a biologic structure, in this case the hip. As a hypothesis of the work, the possibility that changes could be explained following the Lamarckian paradigm, opposed to the Darwinian paradigm, is shown. The section material and methods of this work have been published in part I.
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