Publications by authors named "D Moynan"
Objectives: Periprosthetic joint infection (PJI) is a complication of joint arthroplasty and is seen in 1-2% of cases. Since its initiation in 2013, the national outpatient parenteral antimicrobial therapy (OPAT) program has facilitated the outpatient management of intravenous antimicrobials for PJI. This study aims to describe the clinical epidemiology of patients on OPAT with PJI between 2013 and 2021.
View Article and Find Full Text PDFObjectives: Mal'aria is a parasitic infection that continues to present significant morbidity and mortality figures throughout the world. In the Republic of Ireland (Ireland), mal'aria is an imported infection linked most frequently to travel routes from West Africa. There is a paucity of data on the clinical epidemiology and hospital service utilization of mal'aria in non-endemic setting to inform physician practice.
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- Cytomegalovirus (CMV) significantly impacts solid organ transplant recipients (SOTRs), with secondary prophylaxis (SP) potentially beneficial in high-risk cases despite not being widely recommended.
- A review of studies up to September 2023 found that while SP with valganciclovir did not notably reduce CMV relapse, it was linked to decreased mortality rates among recipients.
- The overall evidence from six nonrandomized studies is insufficient to make definitive recommendations on SP, highlighting the importance of personalized risk assessments by clinicians.
Antimicrobial associated encephalopathy (AAE) is a well-documented, though under recognised, adverse event associated with antimicrobial use. Clinical manifestations of AAE are varied, ranging from myoclonus and seizure to an encephalopathy with cerebellar signs. The phenotypic presentation of the encephalopathy syndrome is, in general, governed by the antimicrobial in question.
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