Publications by authors named "D Moriconi"
Article Synopsis
- Postprandial hypoglycaemia (PPHG) is a common complication after Roux-en-Y gastric bypass (RYGB) in individuals with a history of type 2 diabetes, often occurring without symptoms.
- A study of 24 patients showed that PPHG results from an excessive clearance of glucose and hyperinsulinaemia, linked to higher insulin sensitivity and enhanced beta cell function.
- Those experiencing PPHG had poor hormonal responses to low blood sugar, leading to more frequent and prolonged hypoglycaemia, which affected their eating habits over time.
Introduction: post-bariatric hypoglycemia (PBH) is considered a chronic complication after gastric bypass (RYGB) impacting roughly 30 % of patients. Current treatments often focus on nutritional interventions to reduce the frequency of episodes. This prospective study evaluated the effectiveness of Lisosan G (LG), a fermented wheat-based supplement added to the diet, in mitigating PBH episodes and elucidating its mechanism of action on the gut-pancreas axis.
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- This study investigates how fluctuations in heart rate (HR) over a 24-hour period relate to microvascular disease and survival in diabetes patients.
- It involved a cohort of 349 adults with diabetes, examining those with low HR fluctuations and reduced nighttime HR dip, highlighting their connection to worse cardiovascular health outcomes.
- The findings suggest that impaired HR patterns are linked to higher risks of cardiovascular and overall mortality, indicating that HR monitoring could help assess risk in diabetic patients.
Role of endogenous GLP-1 on arterial stiffness and renal haemodynamics following bariatric surgery.
Eur J Clin Invest
September 2024
Background: Cardiovascular trials have revealed the positive impact of GLP-1 receptor agonists (GLP-1 RAs) on cardiovascular outcomes in type 2 diabetes (T2D). However, the specific effects of endogenous GLP-1 on arterial stiffness and renal function remain understudied. This study aimed to explore the influence of endogenous GLP-1 response post-bariatric surgery on arterial stiffness and renal haemodynamic.
View Article and Find Full Text PDFBackground: bariatric surgery stands as an effective intervention for weight loss and improved metabolic control in obesity, although over time there is a proportion of weight regain and type-2-diabetes (T2D) relapse.
Aims: to explore the role of physical activity (PA) after surgery and its impact on metabolic parameters during a 5-year follow-up.
Methods: 148 individuals who underwent bariatric surgery completed scheduled examinations over 5-years.