Low-energy laser irradiation reduces formation of scar tissue after myocardial infarction in rats and dogs.

Background: Low-energy laser irradiation (LELI) has been found to attenuate various biological processes in tissue culture and experimental animal models. The aim of the present study was to investigate the effect of LELI on the formation of scar tissue in experimentally induced chronic infarct in rats and dogs.

Methods And Results: Myocardial infarction (MI) was induced in 50 dogs and 26 rats by ligation of the left anterior descending coronary artery.

Testicular neovascularization by "omentotesticulopexy': a possible adjuvant in the surgical correction of high undescended testes.

The surgical repair of "very high" undescended testes may bring about testicular atrophy, as a result of impaired vascular supply, whether caused unintentionally by extensive dissection, or deliberately when the Fowler-Stephens operation is employed. In this experimental study, improvement of the vascular supply by means of "omentotesticulopexy" (an omental flap pexied to the rat testis) before or concomitant with spermatic vessel division (known as the Fowler-Stephens operation) was achieved and demonstrated by angiographic studies. The authors believe that the addition of "omentotesticulopexy" to the Fowler-Stephens operation will reduce the rate of testicular atrophy among patients with high undescended testes.

Jejunal mucosal function of the isolated bowel segment created by omentoenteropexy in dogs: a study by in situ luminal perfusion.

An isolated bowel segment (IBS) was created in dogs by omentoenteropexy, using staged procedures. (1) Omentoenteropexy was performed at the antimesenteric border of a 15-cm jejunal segment, which was exteriorized at both ends (IBSB). (2) After 6 weeks, once dual vascularization to the IBS had been established, its mesentery was divided (IBSA) or longitudinally split, thus achieving its elongation (IBSE).

Tissue precooling for thermochemical damage reduction during laser surgery.

This report describes a preliminary investigation of the possibility of reducing the thermal damage induced by lasers in the course of laser surgery. Skin incisions made by CO2 laser beams--with and without precooling--were evaluated and compared with scalpel cuts. Full thickness cuts were carried out on the flank of adult cats.

Effects of nonischemic hypoxia on jejunal mucosal structure and function: study of an experimental model in dogs.

A model of nonischemic hypoxia of the jejunum was designed in dogs, by shunting of blood from the inferior vena cava directly into the regional mesenteric arterial supply, thereby lowering the PaO2 of the blood that reached the jejunal wall from 98.6 +/- 3 to 62 +/- 5 mm Hg. Absorption rates of sodium, glucose, fructose, glycine, and the dibasic aminoacid lysine were studied by in situ luminal perfusion of a 30-cm proximal jejunal segment with a bicarbonate buffer solution containing phenol red as a nonabsorbable marker for determination of water fluxes.