Influenza a Virus Detection at the Human-Swine Interface in US Midwest Swine Farms.

This study evaluated influenza A virus (IAV) detection and genetic diversity over time, specifically at the human-swine interface in breeding and nursery farms. Active surveillance was performed monthly in five swine farms in the Midwest United States targeting the employees, the prewean piglets at sow farms, and the same cohort of piglets in downstream nurseries. In addition, information was collected at enrollment for each employee and farm to assess production management practices, IAV vaccination status, diagnostic procedures, and biosecurity.

The association between cardiovascular risk and physical performance in individuals with obesity: A cross-sectional study focusing on the 5× sit-to-stand test.

Introduction: Although it is established that individuals with obesity are at increased risk of cardiovascular events, the relationship between cardiovascular risk and physical function in this population is still a topic of discussion. The objectives of the present study were: to check the association between cardiovascular risk and physical performance through physical-functional tests and to identify cutoff points for functional tests to be used for the definition of high cardiovascular risk.

Methods: A cross-sectional study included adults, both sexes, with obesity.

Batzelladine D, a Marine Natural Product, Reverses the Fluconazole Resistance Phenotype Mediated by Transmembrane Transporters in and Interferes with Its Biofilm: An In Vitro and In Silico Study.

Numerous species are responsible for fungal infections; however, stands out among the others. Treatment with fluconazole is often ineffective due to the resistance phenotype mediated by transmembrane transporters and/or biofilm formation, mechanisms of resistance commonly found in strains. A previous study by our group demonstrated that batzelladine D can inhibit the Pdr5p transporter in .