Publications by authors named "D Miric"
Acutely decompensated heart failure is one of the leading causes of hospitalisation worldwide, with a significant majority of these cases attributed to congestion. Although congestion is commonly mistaken for volume overload, evidence suggests that decompensation can occur without significant water accumulation, being attributed to volume redistribution. Yet, the distinction between intravascular and extravascular congestion in heart failure often blurs, as patients frequently exhibit overlapping features of both, and as patients may transition between phenotypes over time.
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- - The SGLT2 inhibitor empagliflozin has been approved for treating all types of heart failure, including the less common bradycardia-induced heart failure with preserved ejection fraction (HFpEF), a condition characterized by heart function maintaining normal pumping ability despite underlying issues.
- - A case study details a 32-year-old woman with no previous medical issues who experienced fatigue and exercise intolerance, leading to a diagnosis of junctional bradycardia and HFpEF, confirmed through various diagnostic imaging and tests.
- - The patient's symptoms improved significantly after treatment with empagliflozin and theophylline, showcasing that bradycardia-induced HFpEF can effectively be managed with these medications even when traditional
Background: The association of percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) on myocardial function, as reflected in myocardial work (MyW) parameters, in patients with ischemic cardiomyopathy and heart failure (HF) is unknown.
Methods: We analyzed data from 68 patients who were hospitalized with chronic HF due to ischemic cardiomyopathy and stratified them according to the mode of revascularization. All patients underwent a 2D speckle tracking echocardiography exam performed by the same expert sonographer and had complete MyW data including global work index (GWI), global constructive work (GCW), global wasted work (GWW), and global work efficiency (GWE).