Publications by authors named "D Mille"
Article Synopsis
- The study focused on individualized dosing of niraparib for patients with platinum-sensitive recurrent ovarian cancer (PSROC), revealing that most patients required treatment modifications due to adverse events (AEs) during the first three months.
- A significant proportion of patients (62%) experienced AEs, with common issues including fatigue, insomnia, and thrombocytopenia, highlighting the physical and emotional burden of the therapy.
- The findings indicated that physicians often underestimated these symptoms, emphasizing the importance of patient self-reporting for a comprehensive understanding of treatment-related challenges.
Aim: To evaluate R0/R1 resection rate in patients with colorectal liver metastases (CLM) treated with aflibercept plus FOLFIRI after failure of a prior oxaliplatin-based regimen in daily clinical practice.
Methods: This French, multicentre, prospective, observational cohort (NCT05178745) included patients with CLM (alone or predominant; up to 5 lung nodules <2 cm allowed) initiating aflibercept plus FOLFIRI every 2 weeks per physician choice. Primary endpoint was R0/R1 resection rate.
Background: The European Society of Cardiology (ESC) guidelines recommend a dynamic (0-1h) cardiac troponin (cTn) determination for non-ST elevation myocardial infarction diagnosis. For patients with low cTn levels, a discharge from emergency can be considered. Nevertheless, cTn cutoffs for discharge are lower than the limits of quantification proposed by laboratory reagent suppliers.
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- The discharge of high pH effluent from the Gardanne alumina plant in France creates underwater concretions and a plume of white particles at a depth of 324 m.
- Major elements in these concretions include magnesium (Mg) and aluminum (Al), with additional elements like calcium (Ca) and sulfur (S) present in lower concentrations, while environmental concerns focus on the trace elements arsenic (As) and vanadium (V).
- Particle size analyses show that most of the main elements are found in particles with diameters between 15.6 and 63 μm, which make up 53-60% of the total mass of the concretions and have settling rates of approximately 96 m/day.
Objectives: To describe the French routine use of G-CSF in patients treated for breast cancer as per the EORTC recommendations.
Patients And Methods: A prospective multicenter observational study conducted between February 2008 and September 2009 in 869 breast cancer patients treated by chemotherapy (CT) and for whom G-CSF treatment will be delivered in primary (PP) or secondary prophylaxis.
Results: The mean age was 55 years.