Publications by authors named "D Metodiev"

Article Synopsis
  • * A case study describes a 41-year-old man with malignant melanoma who developed acute paraplegia due to a fracture in his spine caused by a metastatic lesion.
  • * Emergency surgery successfully relieved his spinal compression, leading to a quick recovery in motor and sensory functions, emphasizing the importance of early diagnosis and treatment in such cases.
View Article and Find Full Text PDF
Article Synopsis
  • - The study aims to explore various prognostic factors like age, hormonal status, histological results, and lesion characteristics that influence the outcomes of patients undergoing LLETZ treatment for cervical precancerous lesions.
  • - Conducted between January 2017 and July 2021, the prospective study involved 189 patients and highlighted significant correlations between targeted biopsy results and colposcopic diagnoses concerning the final histological results after the LLETZ procedure.
  • - Findings indicate that factors such as cervical lesion size and type are crucial in predicting the histological outcome, with larger lesions linked to higher risks of HSIL and cervical cancer.
View Article and Find Full Text PDF
Article Synopsis
  • A 9-year-old boy in Bulgaria had a rare brain issue called MOGHE, which caused him really bad seizures since he was 3 years old.
  • Doctors discovered unusual brain activity in specific areas using special scans.
  • After surgery to remove parts of his brain, he is now 18 months seizure-free and doesn't need any medication anymore!
View Article and Find Full Text PDF

As the main treatment modality of central neural system germinomas is radiotherapy and/or chemotherapy, the exact initial diagnosis of the disease is crucial. Depending on the different national protocols, histologic verification can be obligatory in some instances. This is a serious challenge, taking into account the usual location and nonspecific macroscopic appearance of these lesions.

View Article and Find Full Text PDF

Adenomyosis and endometriosis are distinct gynecological disorders characterized by ectopic growth of endometrial tissue. Their etiology remains unclear, but stem cells have been implicated in both. The aim of this study was to investigate and compare the quantity of NOTCH1+ and CD117+ stem cells in endometriosis and adenomyosis lesions.

View Article and Find Full Text PDF