Publications by authors named "D Melamed"
Beyond the common comorbidities related to obesity, such as type 2 diabetes and cardiovascular diseases, impaired lung function is already known, but whether the fat distribution (sub-cutaneous, visceral) affects the lung function and pulmonary immune response are poorly known. Few evidence has shown that visceral fat is associated with insulin resistance, low-grade inflammation, and reduced lung function. In the present study, the body composition and fat distribution were evaluated by multi-frequency octopolar bioimpedance.
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- Aging leads to a decline in cardiovascular health, which might worsen due to low caloric intake, but this relationship hasn't been thoroughly explored in older adults.* -
- In a study of 61 older adults, those on a hypocaloric diet showed decreased functional capacity and fewer sit-to-stand repetitions but improved cardiovascular metrics such as stroke volume and vascular resistance.* -
- Ultimately, while a long-term low-calorie diet seemed to boost cardiovascular function in healthy older adults, it negatively impacted their physical performance without affecting immune system markers.*
Aim: Physical activity attenuates hypertension in older adults, but its impact on pulmonary function and mechanics in hypertensive older adults is unknown. The study seeks to understand whether a physically active lifestyle can improve respiratory capacity, the mechanical efficiency of the lungs, and, consequently, the quality of life of these individuals, comparing data between groups of active and sedentary hypertensive older adults.
Methods: This is a cross-sectional study.
Article Synopsis
- Asthmatic children have higher levels of pro-inflammatory and pro-fibrotic mediators, leading to increased airway resistance and impaired lung function compared to non-asthmatic children.
- A study involving 78 children (39 asthmatic and 39 non-asthmatic) revealed significant differences in immune response and respiratory mechanics, with asthmatic children showing a marked increase in various blood cells and specific inflammatory factors.
- The research suggests that using impulse oscillometry can effectively measure airway resistance in asthmatic children, highlighting its importance in assessing and managing asthma severity.
Experiencing trauma in childhood is a global public health issue linked to worse physical and mental health outcomes, including Post-Traumatic Stress Disorder (PTSD). Self-concept is a transdiagnostic concept linked to various psychopathologies and understanding its unique relationship to trauma is important. This meta-analysis aimed to understand the size of the effect between trauma and maltreatment and self-concept in children and adolescents.
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