Publications by authors named "D Medic"

Article Synopsis
  • A rare case of a mycotic abdominal aortic aneurysm was reported in a 68-year-old male, linked to a specific pathogen, highlighting its unusual association with severe vascular infections.
  • The patient presented with severe abdominal pain, and imaging revealed a significant aneurysm, which was successfully surgically removed and treated with targeted antibiotics after identifying the pathogen from the aneurysm wall.
  • The case underscores the need for better guidelines and surveillance for vascular infections caused by this pathogen, particularly in immunocompromised patients.
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The currently dominant SARS-CoV-2 omicron variant, while causing mild respiratory symptoms, exhibits high transmissibility, drug resistance, and immune evasion. We investigated whether the presence of the SARS-CoV-2 affected the dynamics of fecal microbial composition isolated in culture in moderate COVID-19 patients. Blood, stool, and medical records were collected from 50 patients with confirmed SARS-CoV-2 infection.

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Background: Carbapenem-resistant Enterobacterales (CRE) bloodstream infections (BSIs) are a major threat to patients. To date, data on risk factors have been limited, with low internal and external validity. In this multicentre study, risk factors for CRE BSI were determined by comparison with two control groups: patients with carbapenem-susceptible Enterobacterales (CSE) BSI, and patients without Enterobacterales infection (uninfected patients).

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Non-tailed icosahedral phages belonging to families Fiersviridae (phages MS2 and Qbeta), Tectiviridae (PRD1) and Microviridae (phiX174) have not been considered in detail so far as potential antibacterial agents. The aim of the study was to examine various aspects of the applicability of these phages as antibacterial agents. Antibacterial potential of four phages was investigated via bacterial growth and biofilm formation inhibition, lytic spectra determination, and phage safety examination.

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