Publications by authors named "D McIntosh William"
The nutritional and functional properties of squashes are influenced by various factors, such as the stage of plant development, soil composition, and type of fertilizer. This study evaluates the impact of various organic fertilizers on D. properties.
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- Whole Exome Sequencing (WES) is a powerful tool in cancer diagnostics that allows for comprehensive analysis of genes, improving the detection of complex biomarkers compared to traditional panel-based methods.
- A study analyzing tissue specimens across 21 NGS centers showed that, although there was a 76% agreement in somatic variant calling, refining filtering criteria improved this to 88%, highlighting the importance of filter settings in variant detection.
- The reliability of detecting specific genomic changes (like CNAs and complex biomarkers) varied among labs, emphasizing the need for improved bioinformatics processes and collaborative testing to minimize discrepancies in future analyses.
Complete remission of BRAF V600E-driven ACC CUP by BRAF/MEK inhibition underscores importance of precision oncology.
View Article and Find Full Text PDFBackground: Clear cell renal cell carcinoma (ccRCC) is the most common subtype of RCC with high rates of metastasis. Targeted therapies such as tyrosine kinase and checkpoint inhibitors have improved treatment success, but therapy-related side effects and tumor recurrence remain a challenge. As a result, ccRCC still have a high mortality rate.
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- Patient-centered, culturally sensitive healthcare is crucial in low and middle-income countries (LMICs) like Indonesia, as cultural beliefs significantly influence health behaviors and outcomes.
- In Indonesia, incorporating communal collaboration, family involvement in decision-making, and spiritual beliefs into healthcare practices empowers patients and enhances their well-being.
- Effective strategies for health behavior change include community-based interventions, culturally sensitive communication, patient education, and tailored behavior modification techniques that respect and integrate local cultural practices.