Estimating the Budget Impact and Joint Replacement Avoidance by Implementing a Standardized Education and Exercise Therapy Program for Hip and Knee Osteoarthritis in a Publicly Insured Healthcare System.

Objective: Estimate the budget impact of funding a standardized education and exercise therapy program (GLA:D®) for people with hip and knee OA waiting for total joint replacement (TJR) consultation in a universal publicly insured healthcare system in Canada.

Methods: We built a budget impact analysis (BIA) model to estimate the annual cost of providing GLA:D® program to people waiting for TJR consultation and then forecasted a three-year budget cycle. The base case assumes 40% attend GLA:D®, 11% avoid surgery, uniform care delivery, training costs are incurred separately, and the healthcare system has enough trained staff to meet demand.

RETRACTED: De Vecchis et al. Vasopressin Receptor Antagonists for the Correction of Hyponatremia in Chronic Heart Failure: An Underutilized Therapeutic Option in Current Clinical Practice? 2016, , 86.

The retracts the article "Vasopressin Receptor Antagonists for the Correction of Hyponatremia in Chronic Heart Failure: An Underutilized Therapeutic Option in Current Clinical Practice [...

Data-Driven Insights through Industrial Retrofitting: An Anonymized Dataset with Machine Learning Use Cases.

Small and medium-sized enterprises (SMEs) often encounter practical challenges and limitations when extracting valuable insights from the data of retrofitted or brownfield equipment. The existing literature fails to reflect the full reality and potential of data-driven analysis in current SME environments. In this paper, we provide an anonymized dataset obtained from two medium-sized companies leveraging a non-invasive and scalable data-collection procedure.

Pros and Cons of Dietary Vitamin A and Its Precursors in Poultry Health and Production: A Comprehensive Review.

Vitamin A is a fat-soluble vitamin that cannot be synthesized in the body and must be obtained through diet. Despite being one of the earliest vitamins identified, a complete range of biological actions is still unknown. Carotenoids are a category of roughly 600 chemicals that are structurally related to vitamin A.

Effects of Etomidate on Postintubation Hypotension, Inflammatory Markers, and Mortality in Critically Ill Patients with COVID-19: An International, Multicenter, Retrospective Study.

Objective: To evaluate the association of etomidate with postintubation hypotension, inflammation, and mortality in critically ill patients with COVID-19.

Design: International, multicenter, retrospective study.

Participants: Critically ill patients hospitalized specifically for COVID-19 from three major academic institutions in the US and Europe.