Publications by authors named "D Mazzara"

Article Synopsis
  • * A study examined 100 male dogs over a period of 14 months, finding that 6% tested positive for D. repens in their testes, with microfilariae present in 15 blood samples, leading to a total prevalence of 16%.
  • * No harmful lesions or pathological changes were observed in the testes of infected dogs, indicating that the presence of these parasites doesn't usually cause significant health issues, highlighting the need for better monitoring in areas where the parasite is common to prevent transmission to humans.
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Article Synopsis
  • The C(-344)T polymorphism in the CYP11B2 gene, associated with hypertension and cardiac issues, was studied in a young adult population to evaluate its effects on cardiovascular health.
  • Among 420 Caucasian students, anthropometric data and cardiovascular measurements were collected, and the genotype was analyzed.
  • Results indicated a minor influence of the C(-344) allele on systolic blood pressure in males and interventricular septum thickness in females, suggesting that while the polymorphism has some impact, its significance may vary with age.
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Objectives And Design: Angiotensinogen (AGT) gene variants influence angiotensinogen plasma levels in children and young adults. The angiotensinogen promoter (-6)A variant facilitates gene transcription in human tissues and it has been associated with high blood pressure in older adults. A young adult population can be used as a model to study genotype/phenotype associations between AGT (-6) variants and cardiovascular variables.

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It has recently been shown that ischemia in collateral-dependent myocardium may develop at a very variable threshold in anginal patients; accordingly, the aim of this study was to assess whether nifedipine and diltiazem can increase blood flow to collateralized myocardium in man. Nine patients with complete coronary occlusion filled by collaterals, with no other coronary stenosis, normal left ventricular function, and reproducibly positive exercise tests were studied. They underwent exercise tests off therapy and after acute randomized administration of nifedipine (10 mg sublingually), diltiazem (120 mg orally), and nitroglycerin (0.

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Background: The effects of long-term treatment with gallopamil 50 mg t.i.d were assessed in 8 patients, 7 males and 1 female, aged 47-69 years, with stable angina pectoris, positive exercise tests, coronary artery disease and no previous myocardial infarction.

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