Publications by authors named "D Mazur"
N,N'-Dialkylimidazolium-based ionic liquids are capable of completely dissolving lignocellulosic biomass at elevated temperatures and are considered as promising green solvents for future biorefining technologies. However, the obtained ionic liquid lignin preparations may contain up to several percent nitrogen. This indicates strong interactions between the biopolymer and the IL cation, the nature of which has not yet been clarified.
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- Glutamine is crucial for tumor growth, and its deprivation in solid tumors can hinder their growth and spread, particularly in human glioblastoma cell lines U87MG and T98G.
- Research indicates that U87MG cells, which have a more differentiated phenotype, show increased glycolysis and stemness marker expression (CD133) when deprived of glutamine, while T98G cells shift towards oxidative phosphorylation and become less responsive to certain drugs.
- The study highlights that metabolic and phenotypic differences between these glioblastoma cell lines lead to varying drug sensitivities, suggesting that treatment strategies should consider these differences for better outcomes.
It is well established that breastfeeding provides significant health benefits for both the mother and the infant. The World Health Organization recommends initiating breastfeeding within the first hour after birth and continuing exclusive breastfeeding for 6 months. Successful breastfeeding is influenced not only by the proper physiological preparation of the body and the action of pregnancy-related hormones but also by the mother's overall health status.
View Article and Find Full Text PDFBackground: Patients undergoing primary total knee arthroplasty (TKA) who have a history of meniscectomy have worse postoperative functional outcomes, increased rates of early postoperative complications, and higher revision rates. Despite knowing this, to the best of our knowledge, it has not been previously studied whether the timing of meniscectomy before TKA impacts functional outcomes after undergoing TKA. Compared to patients who underwent meniscectomy more than one year before TKA, do patients who have meniscectomy less than one year before TKA have significantly different postoperative outcomes?
Methods: A retrospective cohort study was conducted at an academic medical center.
Article Synopsis
- The study focuses on creating new cancer-fighting agents by combining ruthenium complexes with the drug abiraterone acetate to utilize the strengths of both.
- The resulting compounds show strong anti-cancer effects on cancer cells while sparing normal fibroblast cells, indicating selectivity.
- One specific compound, dichlorido(η6-p-cymene)(abiraterone acetate)ruthenium(II), demonstrated significantly better anti-cancer activity and induced apoptosis more effectively than abiraterone alone, suggesting it could be a promising candidate for further research.