Publications by authors named "D Mazloomdoost"
Importance: This review aimed to describe research initiatives, evolution, and processes of the Eunice Kennedy Shriver National Institute of Child Health and Human Development-supported Pelvic Floor Disorders Network (PFDN). This may be of interest and inform researchers wishing to conduct multisite coordinated research initiatives as well as to provide perspective to all urogynecologists regarding how the PFDN has evolved and functions.
Study Design: Principal investigators of several PFDN clinical sites and Data Coordinating Center describe more than 20 years of development and maturation of the PFDN.
Introduction And Hypothesis: Standardized digital rectal examination (DRE) correlates with anorectal manometry (ARM) measures. However, less is known about the relationship between DRE/ARM measures and patient-reported outcomes (PROs), especially among women with fecal incontinence (FI). Our aims were to evaluate associations between DRE and ARM measures and compare PROs with diagnostic evaluation measures for women with FI.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the relationship between the urinary and vaginal microbiomes and the severity of urinary incontinence in women with mixed urinary incontinence, based on existing findings about microbiome differences in this group compared to controls.
- Researchers collected urine and vaginal samples from participants and assessed microbiome diversity, alongside measuring incontinence severity using bladder diaries and questionnaires.
- The analysis focused on identifying specific microbiome community types and their associations with incontinence severity, considering factors like age and body mass index in the evaluation.
Importance: The optimal surgical repair of vaginal vault prolapse after hysterectomy remains undetermined.
Objective: To compare the efficacy and safety of 3 surgical approaches for vaginal vault prolapse after hysterectomy.
Design, Setting, And Participants: This was a multisite, 3-arm, superiority and noninferiority randomized clinical trial.
Background: Many clinical trials use systematic methodology to monitor adverse events and determine grade (severity), expectedness, and relatedness to treatments as determined by clinicians. However, patient perspectives are often not included in this process.
Objective: This study aimed to compare clinician vs patient grading of adverse event severity in a urogynecologic surgical trial.