Antigenicity of cortical bone allografts in dogs and effect of ethylene oxide-sterilization.

The aims of the present study were to determine the antigenicity of cortical bone allografts and the effect of ethylene oxide-sterilization (EO-sterilization). Cortical bone allografts from one donor dog were implanted in a muscle pouch in four groups of four dogs each. The grafts were either fresh, EO-sterilized, demineralized or demineralized and EO-sterilized.

Sufentanil and nitrous oxide anaesthesia for the recording of transcranial magnetic motor evoked potentials in dogs.

Transcranial magnetic motor evoked potentials were recorded from the extensor carpi radialis muscle of the forelimbs and from the cranial tibial muscle of the hindlimbs of anaesthetised dogs. The dogs were premedicated with droperidol and fentanyl and a light plane of anaesthesia was induced and maintained with sufentanil and nitrous oxide. The potentials recorded under sufentanil and nitrous oxide anaesthesia were suppressed in comparison with baseline recordings under droperidol and fentanyl sedation: their latencies were significantly increased and their amplitudes significantly decreased (P < 0.

Comparison of two techniques of narcotic-induced anesthesia for use during recording of magnetic motor evoked potentials in dogs.

Objective: To compare 2 types of narcotic-induced anesthesia for recording of transcranial magnetic motor evoked potentials (TMMEP) in dogs.

Design: The effect of different doses of sufentanil and midazolam and of sufentanil and nitrous oxide on onset latencies and peak-to-peak, amplitudes of TMMEP was evaluated and compared.

Animals: 18 neurologically normal dogs.

A tremor syndrome with a central axonopathy in Scottish terriers.

A central axonopathy in 2 male and 1 female Scottish Terrier puppies from 3 different but related litters is reported. Clinical signs consisting of severe whole-body tremors and ataxia were first detected at the age of 10 to 12 weeks. They worsened with activity and excitement and diminished during rest or sleep.

Liquid chromatographic determination of ampicillin in bovine and dog plasma by using a tandem solid-phase extraction method.

The determination of ampicillin in plasma and serum by reversed-phase high-performance liquid chromatography with UV detection suffers from poor selectivity and sensitivity. Currently, the most common approach to overcoming these problems consists of improving the compound's detectability via pre- or postcolumn derivatization. In the method that we describe, however, enhanced selectivity is afforded by sample purification by a tandem solid-phase extraction method (ion-exchange and reversed-phase).